Progast® FloraCare Drops – Real Ingredients

Progast® FloraCare Drops is a natural product of pharmaceutical grade quality scientifically formulated in a vitamin E oil-based liquid. Our novel formulation is particularly beneficial and safe for use by pregnant and breastfeeding mothers, infants and babies.

Ingredients per 0.2 ml (5 drops)

1. Lactobacillus reuteri, (strain 1E1) 100 million (1 x 108) live, freeze dried Colony Forming Units (CFU)

The administration of the specific probiotic strain L. reuteri, may prevent colic, regurgitation and constipation.1,2 In acute diarrhea L. reuteri has been helpful to significantly reduce the frequency of watery diarrhea in infants and toddlers.3

L. reuteri, assists in the absorption of food, accelerates gastric emptying and increases the number of stools,4 reduces distension and lessens the frequency of regurgitation.5

The results of a study,6 suggest a useful role for L. reuteri supplementation in improving feeding tolerance and gut function in formula-fed preterm newborns. L. reuteri plays an important role in helping babies to digest breast milk and solids foods.

This is an important probiotic strain in the prevention and management of colic. L. reuteri, minimises gut discomfort such as bloating, wind and constipation as it increases transit time by improving bowel movements. For more on colic, visit our conditions page.

Throughout life, the bacteria supports the integrity of the gut lining and improve immune response. L. reuteri has been shown to protect against the pneumonia virus.7  In a study to show how probiotics improve immunity, significantly fewer incidences of cold and flu was reported in the probiotics investigational group than the placebo group.8

A promising area of research is the use of probiotic supplementation in pregnancy and infants in the first 6 months of life, to reduce skin rashes in babies by 50%!9

2. Vitamin D3 (400 IU) 10.000 µg

Vitamin D has an effect on the developing immune system, reduces inflammation, promotes calcium absorption in the gut and enable normal mineralisation of bone. Vitamin D lowers the prevalence of a common cold and ear infections. Low levels of vitamin D are associated with upper and lower respiratory infections, asthma and inflammatory bowel conditions.

Vitamin D assists with bone mineralisation and effective calcium absorption for bone formation.

Populations especially at risk for low vitamin D status are infants, children, pregnant and postmenopausal women. Besides the classical diseases such as rickets and osteoporosis, vitamin D deficiency in women might be associated with lower fertility and an increased risk for adverse pregnancy outcomes.

Vitamin D plays an important role in fetal programming. It induces more than 3 000 genes, many of which have a role in fetal development. Therefore, vitamin D may be particular relevant to the ‘developmental origins’ in which environmental factors such as vitamin D status in the mother, influence the genomic programming of fetal and neonatal developmental and subsequent disease risk in both childhood and adult life.

In later life, children of mothers with low vitamin D serum levels during pregnancy, have a higher risk for developing certain chronic health challenges, such as asthma, schizophrenia, multiple sclerosis, type 1 diabetes mellitus and insulin resistance. This suggests intrauterine programming or fetal epigenetic programming, as possible mechanism.

3. Zinc picolinate 20 mg

Zinc, an essential mineral, helps to regulate our inflammatory response through its role in supporting our immune system. Any deficiency in zinc can have dire consequences, including stunted growth and development, immune dysfunction, and metabolic imbalances.10

Saliva has its own pH buffer system. This can be disturbed by a zinc deficiency. Causing major digestive upsets.

Zinc shortens the duration of colds. A zinc deficiency reduces the immune cells’ ability to function. Inadequate zinc supply leads to inflammation.11 For all these reasons, zinc has a substantial impact on the body’s immune defences. The occurrence of neonatal infections significantly decrease with zinc supplementation, supporting the benefits of zinc supplementation for both mother and developing fetus.12

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References:

  1. MiGL, Zhao L, Qiao DD, et al.Effectiveness of Lactobacillus reuteri in infantile colic and colicky induced maternal depression: a prospective single blind randomized trial.  2015;107(154):1557-1553.
  2. Indrio F, Di Mauro A, Riezzo G, et al. Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trial. JAMA Pediatr. 2014;168(3):228-233.
  3. Gutierrez-Castrellon P, et al. Diarrhea in preschool children and Lactobacillus reuteri: a randomized controlled trial. 2014;133(4):e904-e909.
  4. Ojetti V, laniro G, Tortora A, et al. Effect of Lactobacillus reuteri. supplementation in adults with chronic functional constipation: a randomised double-blind placebo-controlled trial. J Gastrointestin Liver Dis.2014;23:387-391.
  5. Indrio F, Riezzo G, Raimondi F, et al. Lactobacillus reuteri accelerates gastric emptying and improves regurgitation in infants. Eur J Clin Invest. 2011;41(4):417-422.
  6. Indrio F, Riezzo G, Raimondi F, Bisceglia M, Cavallo L, Francavilla R. The effects of probiotics on feeding tolerance, bowel habits, and gastrointestinal motility in preterm J Pediatr. 2008;152(6):801-806.
  7. Gabryszewski SJ, Bachar O, Dyer KD, et al. Lactobacillus-mediated priming of the respiratory mucosa protects against lethal pneumovirus infection. J Immunol. 2011;186:1151–1161.
  8. Zhang H, Yeh C, Jin Z, et al. Prospective study of probiotic supplementation results in immune stimulation and improvement of upper respiratory infection rate. Synth Syst Biotechnol. 2018;3(2):113-120.
  9. Kalliomaki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. 2001;357:1076–1079.
  10. Fischer W et al. Global and regional child mortality and burden of disease attributable to zinc deficiency. European Journal of Clinical Nutrition. 2009;63(5):591–597.
  11. Bonaventura P et al. Zinc and its role in immunity and inflammation. Autoimmunity Reviews. 2015(14)4:277–285.
  12. Nossier SA et al. The effect of zinc supplementation on pregnancy outcomes: a double-blind, randomised controlled trial, Egypt. The British Journal of Nutrition. 2015(114)2:274–285